MSM/TMG (methylsulfonylmethane) & (trimethylglycine)
We added TMG (Trimethylglycine derived from sugar beets) to our pure pharmaceutical grade MSM to
create what we think is one of the best nutritional combinations around! TMG promotes proper
Homocysteine levels and Liver function.
Below you will find more information on MSM/TMG... or you can download and print in Adobe® PDF Document format.
You will need Adobe Acrobat Reader to view the PDF file. You can download it here.
MSM/TMG (methylsulfonylmethane) & (trimethylglycine)
We added TMG (Trimethylglycine derived from sugar beets) to our pure pharmaceutical grade MSM to create
what we think is one of the best nutritional combinations around! Necessary for collagen synthesis: skin, hair, nails keeps cells from becoming rigid, softens tissue (the beauty mineral), and Promotes proper Homocysteine levels and Liver function.
Promotes proper Homocysteine levels and Liver function
Support the body with stress, asthma, arthritis, inflammation, constipation, candida
Detoxifies the body
Promotes better blood circulation
Helps muscle & leg cramps, back pain
Permits muscles to heal faster
Promotes energy, alertness. mental calmness, ability to concentrate
Free radical scavenger relieves allergies to foods pollens
Helps liver produce choline
Helps control acidity & ulcers in stomach
Coats intestinal tract so parasites lose ability to hang on
Helps with hypersensitivity to drugs
Support the body's ability to produce insulin important for carbohydrate metabolism
Speeds wound healing
The way nature made it MethylSulfonylMethane is present in most green plant food stuffs and certain algae,
but is destroyed with dehydration and heat. Simply stated, if you cook your food, you're eliminating
important nutritional benefits, including MSM.
Proteins are essential for proper cellular metabolism and soft tissue synthesis. Proper protein synthesis
can only be achieved with alpha-amino acid monomers which maintain the correct molecular framework for
soft and connective tissue throughout the human body.
Because protein is the main ingredient in most soft tissue, beneficial effects from regular use of MSM have
been reported for alleviating arthritis, improved flexibility, smoother skin, healthier hair and nails and
faster and better healing from surgical procedures or traumatic events.
MSM is the transport molecule for elemental sulfur which is required for proper assimilation of the alpha
amino acids methionine and cysteine. In addition, the peptide hormone - insulin requires sulfur in its
molecular structure and numerous other proteins, catalysts, and enzymes incorporate sulfur into their
molecular framework.
For general use, MSM should be taken internally as a food supplement. Topical application of MSM would
penetrate only the immediate epidermal layers of the skin.
For more information: 800/601-7099
Nutritional Significance and Medical Applications of MSM - a biologically active sulfur compound.
ABSTRACT
MSM(methylsulfonylmethane), a naturally occurring dietary derivative of DMSO, serves as an important
source of bIoavailable dietary sulfur and, when administered orally, is effective in ameliorating
symptoms of physiological response to stress including gastrointestinal upset, inflammation of the
mucous membranes, pain associated with musculoskeletal system disorders, and infectant allergens. MSM
appears to augment immunological competence through a natural, vitamin- like moderating or normalizing
activity for various body functions and is noted for its exceptionally non-toxic nature. MSM has proved
useful as a dietary supplement for both children and adults, including geriatric patients.
Methylsulfonylmethane (MSM) is a naturally occurring sulfur containing compound with multiple functions
in the body. MSM is naturally present in body fluids and tissues and is found in milk and a variety of
fruits, vegetables, and grains in small amounts. At low levels of ingestion, it functions as a normal
dietary ingredient and assimilable source of essential dietary sulfur. At higher levels it functions
as a pharmaceutically active agent which can be used safely and effectively for a variety of purposes.
The development of MSM as a dietary supple ment stemmed from research on DMSO (dimethylsulfoxide). As
a stable, odorless dietary metabolite of DMSO, MSM possesses certain biomedical properties similar to
DMSO together with additional biological activity not possessed by DMSO. MSM, unlike DMSO, is a dietary
factor and is free of the unpleasant odor found with the use of DMSO. MSM, like DMSO, enhances urinary
taurine secretion produced by aromatic hydrocarbons in man and neutralizes the toxicity of
anticholinesterases, thereby providing protection against insecticide exposure or ingestion.
NUTRITIONAL IMPLICATIONS OF MSM
MSM, and many precursor compounds which are readily converted to MSM in the body, are found in most
natural, unprocessed foods. However, because of its volatility, it is readily lost when fresh food is
processed and/or stored. Unless the diet consists largely of raw, unprocessed foods, it is unlikely that
sufficient MSM will be ingested to contribute significantly to the daily nutritional sulfur requirements,
thus furthering the high incidence of sulfur- deficient diets which exist globally.
Sulfur plays an indispensable role in human nutrition which is often overlooked. It is responsible for
the conformation of body proteins through the formation of disulfide bonds, thereby holding connective
tissue together. Thiol (i.e. sulfhydryl) groups are vital for the catalytic function of several body
enzymes. To perform these roles, constant intake of assimilable sulfur is needed by the body.
Although MSM has not yet been established to be a vitamin, it does have a vitamin-like moderating or
normalizing activity for various body functions, as there appears to be high correlation between
abnormal physiological symptoms and low MSM blood levels in human beings. Although MSM is found as a
natural constituent of foodstuffs, like vitamin D, the principle supply is believed to be synthesized
by the body using one of its naturally occurring precursor compounds. Also, excretion data show that
MSM occurs in lower concentrations with increasing age. Too low a body concentration of MSM may
potentially result in adverse physical and psychological stress, tissue and organ malfunction,
fatigue, and increased susceptibility to disease.
EFFECTS OF ORAL ADMINISTRATION DIETARY SUPPLEMENTS
Oral preparations of MSM have been found useful in the normalization of body functions in patients
displaying physiological symptoms of stress, particularly those sources of stress which cause
gastrointestinal upset, inflammation of mucous membranes, and allergic reactions. MSM ameliorates
these symptoms thereby permitting more rapid recovery. Conditions which have favorably responded to
oral MSM include the following:
ALLERGIC RESPONSES
MSM has a broad and profound beneficial effect in ameliorating diverse allergic responses. MSM
ameliorates allergic reactions to inhalant, ingestant, contact, and infectant allergens. Subjects
find a direct correlation between concentration of MSM used and resistance to allergens.
Environmental allergies: Subjects with chronic to severe allergies to environmental materials such
as house dust, pollen, wool, animal hair, feathers, and other diverse allergens report substantial
to complete relief of their allergy symptoms. Allergy symptoms ranged from respiratory congestion to
inflammation, itching, mucoid discharges, and general discomfort. Although MSM alone may not totally
eliminate allergic responses, the majority of subjects report a significant reduction in concurrent
anti-allergy medication are required to keep their allergic symptoms to a minimum. Individuals with
allergic asthma or hay fever typically report equivalent or better control of symptoms.
Food and drug allergies: Individuals who manifest an allergic response to drugs, such as aspirin,
non-steroidal anti-arthritic agents (IndocinŽ,MotrinŽ) and oral antibiotics, as well as those who
are mildly to severely allergic to various foods, such as cereals, shrimp and other seafood, milk,
etc., report either a lessened intolerance or a complete tolerance to these substances. Thus, a major
application of MSM may be as a safeguard against allergic response to orally ingested drugs, foods,
or beverages which are allergens or irritants to individuals sensitive to these substances.
GASTROINTESTINAL UPSET
MSM is effective in ameliorating gastrointestinal upset such as that produced by the ingestion of
aspirin and other pharmaceuticals or parasitic infections. Individuals with gastrointestinal symptoms
such as diarrhea, chronic constipation, nausea, hyperacidity and/or epigastric pain, or inflammation
of mucous membranes also will experience dramatic relief.
PAIN FROM SYSTEMIC INFLAMMATORY DISORDERS
Individuals presenting symptoms of pain and inflammation associated with various musculoskeletal
system disorders, including arthritis, reported substantial and long-lasting relief. Most, trying
first MSM alone, then a combination with ascorbic acid, reported greater benefit with the combination.
The use of MSM with ascorbic acid is particularly useful in correcting leg cramps.
MSM is capable of reducing the incidence of or entirely eliminating leg and back cramps, muscle spasms,
and general soreness, particularly in geriatric patients who experience cramps at night or after
long periods of inactivity. It's also effective for athletes who experience severe leg cramps during
sports activity. Migraine suffers also have obtained substantial relief while arthritic patients report relief from
pain and stiffness as well as reduced swelling and inflammation.
PARASITIC INFECTIONS
In vitro and in vivo tests suggest that MSM has ameliorating or curing activity against a variety
of medically important parasitic, microbial, and fungal problems of the intestinal and urogenital
tracts. MSM is active against Giardia lamblia (traveler's diarrhea), Trichomonas vaginalis, Nematodes,
Enterobius and other intestinal worms, systemic infections by Histoplasma capsulation, Coccidioides
Toxoplasm and other in vitro susceptible organisms. MSM may affect such infection by competing for
binding or receptor sites at the mucous membrane surface presenting a blocking interface between
host and parasite. MSM appears to augment immunological competence which may also partly explain its
effectiveness in treating parasitic infections.
These statements have not been evaluated by the FDA (USA).
This product is not intended to diagnose, treat, cure, or prevent any disease.
You should carefully read all product packaging and labels. If you have or suspect that you have a
medical problem, promptly contact your medical professional.
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