In 1950, a non-obese mouse colony, being studied by a non-profit bio-medical research institution, produced a strain of obese offspring. The scientists studying these mice concluded that there must have been a mutation in a hormone which regulates hunger and energy expenditure. They named the theoretical mutation the “ob” (obesity) mutation. These mutated mice also had features of type 2 diabetes

Forty-five years later, follow-up research identified the first fat cell-derived hormone in humans and named it leptin. The researchers proposed that leptin regulated hunger and energy expenditure. Additional research suggested that resistance to leptin was a possibility and therefore a possible cause of obesity.

Since the discovery of leptin, many leptin-related studies have been performed. Some outcomes observed by some of these studies are worth taking notice:

Since the discovery of leptin and its physiological roles, many appetite suppressors and metabolism boosters (aka ‘fat burners’) such as green coffee bean extract, African Mango, and vitamin benfotiamine (a form of vitamin B) have been identified by nutritional scientists. SuperGood Stuff’s vegetarian “Weight-to-Go” supplement contains several ingredients formulated to help lose weight and keep it off. It also has other potential health benefits such as boosting energy level and mental alertness, promoting healthy blood sugar levels, and supporting healthy cardiovascular function just to name a few. You can read its complete list of ingredients at