Benfotiamine is a relative of Thiamine, which is better known as vitamin B1. Thiamine is critical for the metabolism of our brain’s major energy source- glucose. Benfoditamine, which converts to Thiamine in the body, enters cells more easily than Thiamine. 

Benfotiamine is converted to Thiamine, which serves as a key factor for three enzymes involved in generating energy from glucose. Preclinical studies have found that Benfodiatmine enhances cognitive function and reduces biological markets of Alzheimer’s disease. 

These benefits may be due to Benfotiamine's ability to suppress the activity of an enzyme that promotes the progression of Alzheimer’s. It also stimulates the production of an enzyme that helps clean capillaries.

Laboratory studies have shown that Ashwagandha may benefit cognitive function by promoting neuronal growth and protecting neurons from damage and oxidative stress. 

In a randomized controlled study, patients with bipolar disorder treated with 500 mg/day experienced greater improvements in a type of working memory, a measure of reaction time, and a measure of social cognition, compared to those receiving placebo. 

Previous studies have demonstrated consistent supplementation with a proprietary spearmint extract(PSE) can improve cognitive performance in individuals 50-70 years of age with age-related memory issues. 

Lab and animal data suggest that spearmint polyphenols may promote neurogenesis- the growth of brain cells- while protecting existing neurons and boosting neurotransmitter levels. 

The volunteers demonstrated improvements in attention and concentration as early as 2.25 hours after a single dose of spearmint extract- demonstrating just how quickly the cognitive effects start taking place. 

Recent human evidence demonstrates that this tea quickly and sustainably boosts mental focus, attention, and concentration - while supporting a restful sleep at night. 

Preclinical research suggests that ALA scavenges free radicals, reduces inflammation, and may protect brain cells from conditions such as a stroke, Multiple Sclerosis, and Alzheimer’s disease.

ALA’s ability to fight oxidative stress is many times more potent than other better known antioxidants, such as vitamin C or E. Furthermore, studies show ALA helps recycle vitamin C and E, as well CoQ10 and glutathione, a crucial antioxidant for nervous system function.

Low levels of glutathione are implicated in many brain disorders, including Autism, ADHD, and Schizophrenia. ALA also affords antioxidant tissue protection in the cell, outside of the cell, and within cell membranes.

ALA improves energy production within the cell’s mitochondria, aka the “powerhouse”. It readily crosses the blood-brain barrier, and is one of the only supplements to do so. 

Huperzine A acts as a cholinesterase inhibitor - a type of medication that works by improving that works by improving the levels of neurotransmitters in the brain. Small early studies suggest that Huperzine A might improve memory and protect nerve cells, which would slow the cognitive decline associated with Alzheimer’s.